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Recommendations for prophylaxis against Pneumocystis carinii pneumonia for adults and adolescents infected with human immunodeficiency virus. Other rare but serious reactions have included toxic epidermal necrolysis (a life-threatening skin condition), acute liver failure, agranulocytosis (severely low levels of white blood cells), aplastic anemia (when the body stops blood cell production), and other blood-related disorders. Diuresis and hypoglycemia have been reported rarely in patients receiving sulfonamides.
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